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This release utilizes the v.2025-02-07 version of the MOAlmanac database. It includes a fix to a bug that prevented HTML report generation. Specifically, in rare circumstances, the columns sensitive_score_bin_map, resistance_score_bin_map, and prognostic_score_bin_map were not added to the data object for actionable variants, which are used to sort report tables.
This release contains updates to the current and draft versions of the database with FDA oncology approvals from June, July, and August 2025. The change log local to this repository has been removed and pointers now direct to news.moalmanac.org. Release notes will also continue to be available through this repository's Releases.
The Molecular Oncology Almanac cloud portal (portal.moalmanac.org) is currently suspended, and perhaps deprecated, due to Google Cloud's deprecation of the Life Sciences API. It may be revisited at a future date. The algorithm continues to be available through GitHub and Docker Hub.
Welcome to news.moalmanac.org! Here, we will aggregate software releases from GitHub and share project updates. Thank you for your continued support!
This release utilizes the v.2025-02-07 release of the underlying MOAlmanac database. The codebase now supports Python 3.13 with no warnings produced, although we will continue officially using 3.12 for the time being.
Updated current and draft version of the database with FDA oncology approvals from May and June, thus far, 2025.
Updated current and draft version of the database with FDA oncology approvals from April 2025.
In this release, we have normalized therapy_name values to NCI thesaurus (#40) and merged an initial version of the next version of our database (#36), that aims to follow with GA4GH's Genomic Knowledge Standards for the database schema (Read more here).
We are in the process of refactoring and updating moalmanac db to align with GA4GH's Variant Annotation Specification (va-spec) and Categorical Variant Representation Specification (Cat-VRS). Both of these specifications are in development and are following the GA4GH Genomic Knowledge Standards (GKS) Maturity Model. As components of each specification moves from draft to trial and to normative maturity we will update our schema to align with their recommendations. This version of the database is under active development and, if you have any thoughts, comments, concerns, or suggestions, please contact us!
This release utilizes version 2025-02-07 of the underlying moalmanac database and contains changes from several pull requests: #32, #33, #35, and #36.