Molecular Oncology Almanac¶
The Molecular Oncology Almanac is a paired knowledge base and interpretation algorithm for precision oncology. It associates molecular alterations with therapeutic sensitivity, therapeutic resistance and disease prognosis, both for individual events such as somatic variants, copy number alterations, fusions and germline variants, and for global features of a tumor such as tumor mutational burden, microsatellite instability, mutational signatures and whole-genome doubling.
This site documents each part of the project:
| Database | The expert-curated knowledge base, how its records are structured, and a reference page for every schema. |
| API | The public API at api.moalmanac.org, with a reference page for every endpoint. |
| Browser | The web browser at moalmanac.org for searching the database. |
| Algorithm | The clinical interpretation algorithm for individual patient samples, and a description of its inputs and outputs. |
To cite the Molecular Oncology Almanac or a specific database release, see Citation.
For research use only
This database and software have not been validated for diagnostic or clinical use. See the Disclaimer and the Terms of use.